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Peptides with fewer residues are more susceptible to rapid enzymatic degradation, leading to shorter systemic exposure. Fosgerau & Hoffmann, Drug Discovery Today Half-Life Each peptide has a defined biological half-life the time it takes for half of the substance to be eliminated from the bloodstream

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While it has been FDA-approved for medical use in reducing visceral fat in HIV patients, bodybuilders often use it off-label, where long-term safety data is more limited

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